I was short of time yesterday, but can answer longer now.
At 10 weeks old she is still a baby and like all babies they are very vunerable and insecure, they need to have constant contact with mum. Human babies don't like being shut away from mum either, but with the right handling both babies and pups can learn to cope.
It is lovely you can take her to work with you but when she is shut into a room on her own it is very scary. Is it possible for her to be put into a crate instead? This will also help with her socialisation with humans.
Giving her plenty of attention doesn't always work, it has to be the right attention, you need to be teaching her what you want of her, how to behave, good manners etc as well as obedience. For pups clicker training is wonderful, it also builds up their confidence.
You don't have to wait until after her vaccinations to take her out as long as you don't put her on the ground, many experienced dog owners carry the pups in bags so they can socialise them during this time as it is a valuable age for a pup for learning. Due to owners not socialising pups at this time many never learn how to cope when outside and become very fearful so the more she sees the better.
She is chewing because she is investigating, babies put everything into their mouths and chew, pups are the same. Keep out of the way what you don't want her to chew and give her what she can. You can even get puppy teething rings now
Dogs don't pick up house training, they have to be taught what to do, babies don't just pick it up either, we have to train our toddlers. Same with language, we have to teach our babies how to understand English so we have to teach our pups what words mean.
To house train her you need to take her out so you can praise her when she goes, lots and lots and lots of praise.
Take her out when she wakes up, during the day after her naps as well.
Take her out before and after she wakes.
Take her out after you have been playing with her or had a training session.
At 10 weeks old she needs taking out every half an hour in between, like babies she hasn't developed enough to hold it. The average age for toddlers to become clean and dry is nearly 2, before this they are not developed enough, thankfully dogs develop quicker than this
If you can get to Shoreham and Gill's classes you will get a lot of help and advice, Gill really is good and I owe her a lot, it was Gill who put me on the right track for getting Joe to recall, he had been beaten for coming back and was terrified, she took the trouble to work out what would work with him and what wouldn't.
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